Ozone Therapy Cost: Prices by Treatment (2026)

The short answer: in the US, a standard IV ozone session (major autohemotherapy, or MAH) costs about $200 to $300. Ozone injections run about $100 to $300 per site, an ozone sauna session about $50 to $150, and a rectal session in a clinic about $30 to $100. High-dose IV forms cost more: 10-Pass about $700 to $1,500 and EBOO about $1,800 to $4,000 per session. Doing it at home costs roughly $1,900 to $2,400 once for the equipment and an oxygen tank, then cents per session plus oxygen refills.

Want it done by a clinic? Find an ozone doctor near you. Search by city, state or ZIP, pick the method you want in the filter, and compare what each clinic lists. Prices are set by each clinic, so ask for the per-session price and the total for a full series before you book. Can't afford clinic care? The free ozone therapy guide explains the home methods, safety and equipment.

Prices below are typical US figures reported by practitioners, checked October 2026. They are ranges, not quotes.

Ozone therapy prices by treatment

We don't have a typical price for dental ozone, so ask the dentist what it adds to the visit. Pregnancy rules out ozone therapy. G6PD deficiency is a consideration for MAH (your provider adjusts the dose and monitors you) and rules out HiDose, 10-Pass and EBOO.

What a full course costs

Per-session prices understate the bill, because ozone is almost always given as a series. Using the ranges above:

• IV ozone (MAH), 4 to 8 sessions: roughly $800 to $2,400.
• Injections, 3 to 6 sessions: roughly $300 to $1,800 per site.
• Ozone sauna, 6 to 10 sessions: roughly $300 to $1,500.
• EBOO, 6 to 10 treatments: roughly $10,800 to $40,000.

A clinic that charges $250 a session for 5 sessions ($1,250) can cost less than one that charges $200 a session and recommends 8 ($1,600). Compare the total course, not the per-session price. Many people start with standard IV ozone, which costs the least of the IV forms and has the most research behind it. Insurance rarely covers ozone therapy. In some cases injections done by a licensed physician may qualify for an HSA or FSA, so check with your plan.

What it costs to do ozone at home

Home ozone therapy is a one-time equipment cost. A quality home ozone generator runs about $1,750. Accessory sets for rectal, ear, ozone water and other home methods add roughly $50 to $450, depending on how many methods they cover (compare options in our ozone machine comparison). Oxygen is separate: a medical oxygen tank costs about $100 to $150 to buy or lease and refills about $15 to $20. That puts a complete home setup at roughly $1,900 to $2,400. After that each session costs cents. Compared like with like, rectal ozone at a clinic runs about $30 to $100 a session, so a month of sessions three times a week (12 sessions) is roughly $360 to $1,200, and the same home setup also covers ear, water and limb-bag methods. Home methods do not replace IV ozone, which is done only in a clinic.

Be careful with very cheap machines. Generators under about $200 are usually air purifiers and are not built for therapy. In our experience, generators under about $1,000 are where corners get cut on materials. Read what makes a generator medical grade, and why cheap units fail and how to choose a home ozone machine. For methods, safety and where to start, get the free ozone therapy guide, and see every home method compared.

Why ozone therapy prices vary

• Region. Big-city and coastal clinics usually charge more than clinics in smaller markets.
• Provider type. A physician's office, a naturopathic or integrative clinic, a wellness spa and a dentist price the same method differently.
• Series length. The per-session price may fall with a package, and the total depends on how many sessions you need.
• What's included. Check whether the price covers the consultation, lab work such as G6PD testing, IV supplies, add-ins like vitamin C or glutathione, and follow-up visits.
• Equipment and time. EBOO machines are mostly sold by quote; a rough estimate, pending confirmation, is $15,000 to $60,000 (see EBOO machine price). EBOO also needs a single-use filter set and 45 to 90 minutes of staff time, which is why it costs several times what MAH does.

Find a clinic near you

The Find an Ozone Doc directory lists more than 1,300 US clinics that offer ozone therapy on their websites. Search your city, state or ZIP, filter by method (IV ozone, EBOO, 10-Pass, injections, rectal or ear insufflation, sauna, dental), and message a clinic from its profile. Listings are compiled from public sources and are not an endorsement, so ask each clinic who performs the treatment, what training they have, what the full series will cost, and how they screen for G6PD deficiency and other contraindications. If a clinic isn't close enough, or the price is out of reach, start with the free guide to ozone at home.

If you run a practice and want to add ozone, see our free IV Ozone 101 training.

Frequently asked questions

How much does ozone therapy cost?

About $200 to $300 for a standard IV ozone (MAH) session, $100 to $300 per site for injections, $50 to $150 for an ozone sauna session and $30 to $100 for a rectal session in a clinic. High-dose forms cost more: 10-Pass about $700 to $1,500 and EBOO about $1,800 to $4,000 per session. Each clinic sets its own prices.

How much does an IV ozone therapy session cost?

Standard IV ozone (MAH) is generally $200 to $300 per session, and a series is usually 4 to 8 sessions, so a full course comes to roughly $800 to $2,400.

Why is EBOO so much more expensive than IV ozone?

EBOO machines are mostly sold by quote (a rough estimate, pending confirmation, is $15,000 to $60,000; see EBOO machine price), and each patient needs a single-use filter and gas exchange set, and 45 to 90 minutes of continuous monitoring, so it costs about $1,800 to $4,000 per session. Standard IV ozone (MAH) is simpler, shorter and a fraction of the price, which is why it is the usual starting point.

Does insurance cover ozone therapy?

Insurance rarely covers ozone therapy. In some cases injections performed by a licensed physician may qualify for payment through a Health Savings Account or Flexible Spending Account, so check with your plan administrator.

Is ozone therapy cheaper at home?

Per session, yes. A home setup costs roughly $1,900 to $2,400 once (generator or kit plus an oxygen tank), then cents per session plus oxygen refills at about $15 to $20 each. Rectal ozone at a clinic is about $30 to $100 a session, so the home setup pays back against clinic rectal sessions. It covers home methods such as rectal, ear and vaginal insufflation, ozone water and limb bagging. It does not replace IV ozone, which is done only in a clinic.

How do I find an ozone therapy clinic near me?

Use the Find an Ozone Doc directory: search your city, state or ZIP, choose the method you want, and message the clinic from its profile. Ask about the full price of a series before you book.