Bryce Harper and Ozone Therapy: The EBOO Session He Shared

In the news · October 11, 2026

Philadelphia Phillies star Bryce Harper shared an Instagram video in December 2025 of himself doing EBOO, a clinic-based form of IV ozone therapy, and said it would "improve circulation, reduce inflammation, fight infections, support immune function, remove toxins and increase energy." Here's what he said and what EBOO is.

What did Bryce Harper say about ozone therapy?

In the video, Harper said he had "a great week of wellness starting with this awesome machine," and listed the reasons for the session quoted above. Bleacher Report covered the post on December 6, 2025 [1]. He didn't tie it to a specific injury or to his performance, and we won't either.

What is EBOO?

EBOO stands for extracorporeal blood oxygenation and ozonation. "Extracorporeal" means outside the body. In a session, blood is drawn continuously from a vein in one arm, passed through a filter where it's exposed to a measured mix of ozone and oxygen, and returned through a vein in the other arm. A session usually takes 60 to 90 minutes.

It's the most intensive form of IV ozone and is done only in a clinic, by trained staff, with medical equipment. It isn't a home method. For how it compares with other IV methods, see MAH, HiDose, 10-Pass and EBOO compared, and for cost, side effects and who it suits, see EBOO: benefits, side effects and cost.

Does the research back what he said?

The effects Harper listed match the ones ozone therapy is known for: circulation, inflammation, immune support and energy. The basic biology is explained in how ozone therapy works.

EBOO itself has much less published research than other ozone methods. Most of what exists is case reports and small studies rather than large controlled trials. That doesn't mean it doesn't help. It means the strongest claims haven't been tested well yet, and results vary from person to person.

Can you get similar benefits at home?

EBOO can't be done at home. Many people use home methods such as rectal insufflation between clinic sessions or instead of them, because they cost far less per session. IV vs rectal ozone compares the two honestly, and every home method compared covers the rest. If you’re starting at home, our free guide covers equipment, safety and first steps.

Is it safe?

In trained hands, IV ozone methods have a good safety record. The main risks come from poor technique, unsterile equipment or doses outside standard ranges, which is why practitioner training matters. Read the safety of ozone therapy before booking anything.

For practitioners: MediSkill teaches IV ozone therapy by major autohemotherapy (MAH), which we consider the gold standard of IV ozone. See our IV ozone training.

MediSkill reports what public figures say about ozone therapy. Their comments are their own and aren't an endorsement of MediSkill.

Sources

1. Kasabian P. "Phillies' Bryce Harper reveals why he had blood therapy procedure in new IG video." Bleacher Report, December 6, 2025. bleacherreport.com