Rectal Ozone Therapy Kit and Machine: What You Need and What It Costs

A rectal ozone setup has five parts: an ozone generator, a medical oxygen tank, an oxygen regulator, a 3-chamber ozone bag and a soft catheter. A quality home generator runs about $1,750; SimplyO3's Stratus 3.0 is $1,749.99, and SimplyO3's home kit (generator, regulator and accessories), the Home-User Kit at $1,799.99, adds two bags, ten catheters and syringes. A medical oxygen tank comes from a local gas supplier at about $100 to $150 to buy or lease, so plan on roughly $1,900 to $1,950 to get started.

The oxygen has to come from a tank. An oxygen concentrator does not work for rectal insufflation. This page covers the equipment and what it costs. For how to do it, read rectal ozone therapy and the rectal ozone insufflation protocol. New to ozone at home? Get the free guide.

Prefer a clinic? Rectal ozone at a clinic runs about $30 to $100 a session. Find an ozone doctor near you.

What you need for rectal insufflation

Rectal ozone machine and kit cost

SimplyO3 sells the generator and a kit that covers everything except the oxygen tank. Prices checked October 14, 2026 on simplyo3.com. They change, so check the product page before you buy.

What it adds up to. SimplyO3's home kit plus a tank is about $1,900 to $1,950 to start. After that, the running cost is mostly oxygen: a refill is about $15 to $20, and how long a tank lasts depends on your flow rate and how often you use it. Bags and catheters wear out and get replaced.

Other makers' generators and rectal sets are mostly quote-only. As of October 14, 2026 we couldn't find a published price for a rectal kit from another brand, so call and ask what is in the kit before you compare totals.

Why the oxygen has to be a tank

A concentrator pulls oxygen out of room air and tops out around 90 to 95% oxygen. The rest is mostly argon and nitrogen, and nitrogen passing through an ozone generator forms nitrogen oxides, which you don't want going into your body. For that reason rectal, ear and vaginal insufflation all use medical oxygen from a tank, and room air is out. A concentrator is fine for ozone water and for ozone saunas (see oxygen for ozone therapy).

Why we steer people away from cheap imported rectal ozone machines

Cheap imported generators, often sold on Amazon, eBay or AliExpress, are the main thing we steer home users away from. The reasons are practical:

• Parts that ozone breaks down. Some use brass or other metals and everyday plastics in the gas path. Ozone degrades them, and what they shed ends up in the gas you use (see why materials matter).
• Unverified concentration. Many come with no concentration chart, or one nobody has checked. If you can't trust the dose, you can't follow a protocol.
• No service or support. When it fails, or you have a question, there is often no one to call and no real warranty.
• Questionable “medical” or certification claims. A badge on a listing doesn't tell you what is inside. Ask for the materials list and the paperwork in writing.

Many listings under $200 are air or water purifiers that run on room air and aren't made for ozone therapy. In our experience, generators under about $1,000 are where corners get cut on materials. More in what makes a generator medical grade, and why cheap units fail.

Which generator do you need?

For home rectal insufflation a flow-of-gas generator is enough. You set the concentration with the regulator and the chart that comes with the unit. Dial and digital models are mainly for clinics that do IVs and injections. Dosing and schedule are in the rectal protocol. If you are a clinician adding ozone, see IV Ozone 101.

Related

• Rectal ozone therapy: how it works and how to do it
• Rectal ozone insufflation protocol
• IV ozone vs rectal ozone
• Ozone therapy machine for home: how to choose
• Home ozone kits by method

Frequently asked questions

What do I need to do rectal ozone therapy at home?

An ozone generator, a medical oxygen tank with a matching regulator, a 3-chamber ozone bag (or a syringe), a soft catheter and ozone-resistant tubing.

How much does a rectal ozone machine and kit cost?

SimplyO3's Stratus 3.0 generator is $1,749.99 and its home kit (generator, regulator and accessories), the Home-User Kit, which adds two bags, ten catheters and two syringes, is $1,799.99. A medical oxygen tank is about $100 to $150 to buy or lease, with refills around $15 to $20.

Can I use an oxygen concentrator for rectal ozone?

No. Rectal insufflation needs medical oxygen from a tank. A concentrator's output contains nitrogen and argon, and nitrogen forms nitrogen oxides in the generator.

Can I buy a cheap rectal ozone machine online?

We advise against it. Cheap imports can use parts that ozone breaks down, have unverified concentration, come with no support and make unclear medical claims. Ask for the materials list and warranty in writing.

Where do I get the oxygen tank?

From a local oxygen or industrial gas supplier. Most sellers don't ship oxygen tanks because they are hazardous to ship, so you buy one locally. Ask for a 40 cubic foot tank.

Is there a rectal insufflation kit with everything included?

SimplyO3's home kit (generator, regulator and accessories), the Stratus 3.0 Home-User Kit, includes the generator, regulator, bags, catheters, syringes and tubing. It is a general home kit, not a rectal-specific one, and the oxygen tank is not included.