10-Pass Ozone Therapy: Cost and Equipment for Clinics
10-Pass ozone therapy typically costs patients about $700 to $1,500 per session in the US, compared with $200 to $300 for standard IV ozone (MAH). A clinic that wants to offer it needs an ozone generator, medical oxygen, an ozone-resistant pressurized glass bottle system, sterile lines and catheters, heparin, and a nurse or practitioner watching the patient for the whole session. Makers do not publish prices for 10-Pass equipment, so you get quotes.
If you run a practice, read why we suggest starting with standard IV ozone before you buy 10-Pass equipment.
10-Pass ozone therapy cost for patients
These are the typical ranges US clinics charge per session, from our IV ozone comparison. Prices vary by clinic and location.
| IV ozone method | Typical patient price | Session length |
|---|---|---|
| MAH (standard IV ozone) | $200 to $300 | 20 to 40 minutes |
| HiDose | $400 to $700 | 40 to 60 minutes |
| 10-Pass | $700 to $1,500 | 45 to 90 minutes, with constant monitoring |
| EBOO | $1,800 to $4,000 | 45 to 90 minutes |
Looking for 10-Pass as a patient? Search clinics near you on Find a Doc, and ask each one which protocol they use and how they screen patients. If clinic prices are out of reach, our free guide covers ozone methods you can do at home.
What 10-Pass ozone therapy is
10-Pass (also written 10 pass or ten-pass) draws 200 to 300 mL of blood, mixes it with ozone in a pressurized glass bottle, and returns it to the patient. The cycle repeats ten times, which is where the name comes from. The pressure is inside the bottle; it is not a hyperbaric chamber the patient sits in.
It is unclear whether the extra passes add benefit, although practitioners report good results. There are no good comparative studies against MAH. 10-Pass is nearly as intensive to run as EBOO and usually needs a nurse or practitioner monitoring throughout. G6PD deficiency and pregnancy are absolute contraindications for 10-Pass. See the full IV ozone comparison.
10-Pass equipment for a clinic
Prices checked October 16, 2026.
| Item | What it does | Price |
|---|---|---|
| Hyperbaric medical ozone generator | Makes the ozone and builds the pressure the 10-Pass method needs. Must run on medical oxygen and be calibrated. Examples: Herrmann Hyper Medozon, Zotzmann. | Quote only. Roughly $15,000 to $20,000 new; used units are often listed for $9,000 to $18,000. |
| Single-use pressurized glass bottle sets | Hold the blood while it is mixed with ozone under pressure | About $8 to $12 per set from European dealers. One or more per session. |
| Medical oxygen tank and regulator | Oxygen source. No concentrator or room air for IV ozone. | From a local medical gas supplier. |
| Sterile lines, catheters, heparin, saline | Single-use supplies for each session | Varies by supplier |
| Staff time | A nurse or practitioner monitors the patient the whole session | Your largest ongoing cost |
None of this equipment comes with training.
Because 10-Pass quotes come from specialty suppliers, ask each one what is included, what each session costs in consumables, and what service and support come with the system.
Start with standard IV ozone (MAH), not 10-Pass
10-Pass is an advanced and nuanced protocol, and it takes a significant investment of time. Even if you are set on offering it, it is not the starting place. Start with standard IV ozone (major autohemotherapy, MAH):
- A fraction of the price. A clinic generator for standard IV ozone runs about $5,000, and a standard IV setup needs no specialty pressure system.
- Good results. MAH is the most studied IV ozone method, and clinicians get good results with it.
- Far fewer issues and complications than higher-dose methods.
- Much easier, and far less time per patient. An MAH session takes about 20 to 40 minutes. 10-Pass runs 45 to 90 minutes and needs constant monitoring.
- It may be the only modality you need. For many practices it is. Patients pay $200 to $300 per MAH session against $700 to $1,500 for 10-Pass, so a full series is realistic for more of them.
MediSkill teaches standard IV ozone (MAH) and considers it the gold standard of IV ozone. Full dosing is on the IV ozone protocol page.
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The Definitive Guide to Getting Started with Ozone Therapy: methods, equipment and safety in one place.
Get the free guideFrequently asked questions
How much does 10-Pass ozone therapy cost?
Typically about $700 to $1,500 per session in the US. Standard IV ozone (MAH) is about $200 to $300 per session. Prices vary by clinic.
What equipment does a clinic need for 10-Pass?
A medical ozone generator, medical oxygen with a regulator, a pressurized glass bottle system, sterile lines and catheters, heparin and saline, and a nurse or practitioner to monitor the patient throughout. Makers quote 10-Pass system prices on request.
Is 10-Pass better than standard IV ozone?
No good head-to-head studies show that it is. MAH has the most research behind it, is much easier to run and takes far less time per patient.
Who should not have 10-Pass ozone therapy?
G6PD deficiency and pregnancy are absolute contraindications. Review medications, clotting problems and anemia with a physician first.
How do I find a clinic that offers 10-Pass?
Use Find a Doc to search clinics near you, then ask which protocol they follow and how they screen patients.
Should my clinic start with 10-Pass or standard IV ozone?
Start with standard IV ozone (MAH). It costs a fraction as much, has far fewer complications and takes far less time per patient. For many practices it is the only modality they need.
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