Ozone Therapy for Biohacking and Performance Enhancement

Uses, Benefits, Safety, and How to Do It
Table of Contents

A lot of people want to achieve their physical potential. Maybe you’re one of them. But what does that actually look like? 

  • Living with your highest mental capacity and clarity
  • Avoiding diseases
  • Staying pain free into old age
  • Retaining youthful and attractive looks
  • Staying physically fit and active

To achieve your physical potential is to be unstoppable, crushing both career and personal goals.  It’s to slow and prevent aging, to create a youthful, fit, and attractive body.  

Sound impossible? It’s not. 

Sound like a lot of hard work? You better believe it. 

And no matter what people tell you, there is no magic potion for achieving your physical potential. Living to your maximum physical potential is a lifestyle of deliberate choices. But there are some things that can help you jumpstart (or level up) your journey. 

One of those things is ozone therapy. How? Read on. 

This article covers:

  • How ozone therapy helps you optimize your health 
  • The safety of ozone therapy
  • Best ways to apply ozone therapy
  • How to apply ozone therapy at home


Ozone therapy benefits

Ozone therapy works synergistically with your body by stimulating it on a fundamental level.  It stimulates the NRF2 pathway via mild acute oxidative stress.  This assists with:

  • Increasing energy
  • Modulating the immune system
  • Increasing stamina 
  • Decreasing recovery time
  • Reducing pain and inflammation
  • Reducing brain fog/enhancing mental clarity

IV Ozone for Athletes

Two good studies have been conducted to show the effects of IV ozone therapy for athletes.

The first study included two groups of semi-pro soccer players in Turkey.  The aim of the study was to observe the effects of IV ozone therapy on Vo2 max, indicating endurance and energy.

One group received IV ozone therapy and the other group did not.  

Here is what the study found

“The difference in performance increase was found significant between football players who were treated and not treated with ozone therapy. All athletes performed the same training program for 8 weeks. VO2max was increased 28% in ozone therapy-treated athletes but it was increased 12% in the control group. Max running time was increased 20% in ozone therapy-treated athletes, and it was increased 6% in the control group. In terms of these results, we can say that ozone therapy will be very effective for increasing athletic performance before season or tournaments.”

As you can see, IV ozone produced a significant improvement in Vo2 max over a short 8 week period.  While 28% improvement doesn’t seem like a lot, in young, professional athletes this is a substantial increase and should be cause for consideration of all athletes.

Another study done looked at a similar response.  They observed the effects of ozone therapy on anaerobic threshold, indicating oxygen efficiency.  Someone with a higher anaerobic threshold uses and delivers oxygen to create energy more effectively.

Here is what they found, 

“The fact that a cycle of MAHT had an effect on AT is further evidence of how oxygen-ozone

therapy interacts at several levels. On the one hand the treatment allows the aerobic reserve to be fully exploited by boosting metabolism; on the other it ensures enhanced peripheral delivery of oxygen also by virtue of its effect on erythrocyte 2,3-diphosphoglycerate… In addition to a subjective feeling of well-being and “lightness in the legs”, our athletes had much shorter recovery times. This could be due to both the raised AT and the frequent drop in heart rate during exercise.”

This study indicates that ozone therapy may have a significant impact on athletes:

  • Improved heart rate
  • Improved oxygen delivery
  • Improved energy production
  • Reduced recovery time
  • Improved feeling of wellness

They did note in these studies that athletes typically feel more tired the day after an IV ozone treatment.  This is why athletes should NOT do IV ozone within two days of an important athletic event or game.

Increases energy and stamina

Oxygen is the forgotten nutrient — but it’s also the most important nutrient.  No other nutrient is as necessary to your livelihood as oxygen. 

When oxygen enters your body, it either creates energy or damages cells. (1, 2, 3)

Oxygen efficiency is different from breathing oxygen. Breathing gets oxygen into your body, but oxygen efficiency describes how well you use it.
The big difference between a 20 year old and a 70 year old is how well they utilize oxygen and create energy.  

You can breathe all the oxygen you want (not a bad idea), but how efficiently your body puts that oxygen to use makes all the difference.  Ozone therapy may help people increase their oxygen efficiency.

There is a robust scientific community around ozone therapy.  The scientific literature shows that ozone therapy is versatile, causing a “cascade” effect of positive reactions. Researchers also claim it increases oxygen efficiency and stimulates the body to create more energy.  (4, 5, 6, 7, 8)

By improving your oxygen efficiency, you’re essentially improving all your body systems.  This is why it’s helpful for: 

  • Increasing energy
  • Improving cognitive function 
  • Optimizing metabolism
  • Decreasing recovery time

But this is the miracle of your body, not ozone.  Ozone is just the stimulus to get your body to operate efficiently.  

Dr. Bocci, the Father of Ozone Therapy, wrote about ozone therapy improving oxygen utilization, saying:

“It must be added that ozonated erythrocytes show an improved glycolysis with an increase of ATP… Extensive data have been reported in reviews and two books. It is now clear that a “physiological” ozone dose … triggers an acute and precisely calculated oxidative stress able to activate several biological processes…”

Modulates the immune system

A modulated immune system fights disease more effectively than any drug.  

If your immune system is overactive, as is the case with autoimmune diseases, ozone brings it down to appropriate levels. 

But if your immune system is underperforming, which commonly occurs with mold toxicity, Lyme disease, etc, ozone gives your immune system a boost. (23, 24, 25, 26, 27)

Ozone provides the stimulus for your immune system to balance itself and function appropriately.

(An autoimmune disease, before and after ozone therapy by Dr. Rowen)

Safety of Ozone Therapy

There are millions of ozone therapy treatments done every year, both by home users and over 60,000 doctors worldwide.

Done appropriately, ozone therapy is a safe application.

An adverse event report was published showing a lower adverse event rate than aspirin.

However, ozone cannot be breathed directly into the lungs because they don’t have any antioxidant defenses.  Other parts of the body (blood, vagina, rectum, etc.) have an antioxidant defense system that interacts directly with the ozone and causes a cascade effect, leading to the benefits.

Best Way to Apply Ozone Therapy for Athletic Performance

Intravenous or rectal ozone therapy are the best routes to elicit systemic benefits.

How People Do Ozone Therapy

For less money, people do ozone therapy at home on a daily basis in five minutes or less.  Many reports claim that rectal insufflation is 50 - 95% as effective as the intravenous methods.  Rectal insufflation has a couple other advantages:

  • It can be 5x per week - more ozone therapy!
  • It can be done at home
  • For the price of a few intravenous therapies at the doctor’s, people get their own equipment at home

Total cost for a basic home set up is between $1,400-$2,000 after all is said and done.  


Four steps are involved…

STEP 1: Download the Guide

STEP 2: Get An Oxygen Tank

STEP 2: Buy An Ozone Generator complete Kit

STEP 3: Enjoy the Benefits of Ozone Therapy at Home


Ozone therapy is a viable tool for enhancing the body because it increases oxygen efficiency, modulates the immune system, improves blood flow, and mediates oxidative stress.  I.e. More energy, better recovery, more stamina, and less down time.

Of course, the foundation of health is paramount - good nutrition, water, air, and exercise.  But ozone therapy can serve as a tremendous add on to optimize the body.

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